Medicinal Compounds in Plants and Vegetables Many herbs, medicinal plants, and certain fruits and vegetables contain compounds that can prevent, treat, or reduce the severity of both acute and chronic
Category: Articles
Infectious Disease,Traditional Medicines and MicroemulsionsInfectious Disease,Traditional Medicines and Microemulsions
Introduction to the Problem According to the World Health Organization, global mortality from infectious and somatic diseases—such as HIV, tuberculosis (TB), malaria, cancer, and heart disease—is on the rise. In
How the HIV Virus Takes Over the Immune SystemHow the HIV Virus Takes Over the Immune System
Understanding the Complex Biology and Progression of HIV/AIDS HIV/AIDS remains one of the most complex and deeply studied diseases in modern medical science. To better understand its origins, progression, and
ConclusionConclusion
Rethinking the Immune Response to HIV gp160/gp120 Contrary to conventional assumptions, the appropriate immune response to the HIV membrane proteins gp160 and gp120 may be one of immunological tolerance rather
HIV-induced AutoimmunityHIV-induced Autoimmunity
Autoimmunity and Its Role in AIDS Pathogenesis Substantial evidence supports the hypothesis that autoimmunity plays a fundamental role in establishing the clinical syndrome of AIDS. The HIV viral membrane protein
The Biology of TATThe Biology of TAT
Role of TAT in HIV Pathogenesis TAT is a transactivator protein essential for the initial high-level production of HIV. This early viral output facilitates the generation of mutational variants that
The Biology of VPRThe Biology of VPR
Role of VPR in HIV Pathogenesis VPR is a viral protein specific to primate lentiviruses. Notably, the feline immunodeficiency virus (FIV) lacks a VPR gene, potentially explaining why some infected
The Biology of NEFThe Biology of NEF
Subcellular Localization and Functional Duality of NEF Approximately 95% of the HIV-encoded NEF protein resides in the cytoplasm and nucleus, while the remaining 5% localizes to the plasma membrane. Within
The Induction of Immunosuppression by HIV Viral ParticlesThe Induction of Immunosuppression by HIV Viral Particles
Multifactorial Nature of HIV-Associated Immunosuppression The immunosuppressive effects of HIV infection extend beyond the virus’s direct cytopathic impact on lymphoid cells. Rather than solely the result of viral destruction of
The Enhancing Effects of Physical and Psychology Stress on HIV InfectivityThe Enhancing Effects of Physical and Psychology Stress on HIV Infectivity
HIV Regulatory Proteins and Early Viral Activity The HIV regulatory proteins NEF, TAT, and REV are synthesized in infected cells before the appearance of structural proteins such as GAG and